Pulitzer Prize-winning author Siddhartha Mukherjee, M.D., and acclaimed filmmaker Ken Burns will collaborate on the new documentary inspired by Mukherjee’s best-selling 2016 book, The Gene: An Intimate History. It is to her that this book is dedicated. The atom provides an organizing principle for modern physics—and it tantalizes us with the prospect of controlling matter and energy. The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). The book has drawn intense and mostly positive attention in the mainstream media. The gene, meanwhile, invades discourses concerning race, racial discrimination, and “racial intelligence,” and provides startling answers to some of the most potent questions coursing through our political and cultural realms. Airs Tuesdays, April 7 & 14, 2020 at 8 p.m. on KPBS TV + Fridays, April 10 & 17 at 4 p.m., Saturdays, April 11 … The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a… You may also like. THE GENE: AN INTIMATE HISTORY. Welcome “The Gene: An Intimate History” brings vividly to life the story of today’s revolution in medical science through present-day tales of patients and doctors at the forefront of the search for genetic treatments, interwoven with a compelling history of the discoveries that made this possible and the ethical challenges raised by the ability to edit DNA with precision. The draft sequence of the human genome is published in 2001. $32.. I doubt that I am overstating the case here: our capacity to understand and manipulate human genomes alters our conception of what it means to be “human.”. The 2011 Pulitzer Prize winner, Siddhartha Mukherjee, is back with another incredibly well-written book, The Gene: An Intimate History that unfolds the extensive and profound knowledge and research about human genome and its genetics that reflects beyond the definition of both basic and advanced science. Now in active production, Ken Burns Presents The Gene: An Intimate History, much like the book, will use science, social history and personal stories to weave together a historical biography of the human genome while also exploring the stunning breakthroughs in understanding the impact genes play on heredity, disease and behavior. The annual Wellcome Book Prize celebrates the best new fiction and non-fiction books that engage with an aspect of medicine, health or illness, and each week until the announcement of the winner on 24 April at the Wellcome Collection we will be featuring an extract from the WBP2017 shortlist here on sciencefocus.com. Cold Spring Harbor Laboratory (CSHL) is featured in The Gene: An Intimate History, a Ken Burns documentary premiering on PBS April 7, 2020 (Part 1) and April 14, 2020 (Part 2) at 8 PM ET.. Ken Burns Presents The Gene: An Intimate Story, inspired by Mukherjee’s (pictured left) book of the same name, includes interviews with pioneers in the field and a trove of archival footage. You can unsubscribe at any time. Multiple genetic mutations are identified in human cancers, leading to a deeper genetic understanding of that disease. Scribner. 304 quotes from The Gene: An Intimate History: ‘Freaks become norms, and norms become extinct. IT Irish Theatre Awards; Podcasts. Riveting, revelatory, and magisterial history of a scientific idea coming to life, and an essential preparation for the moral complexity introduced by our ability to create or “write” the human genome, The Gene is a must-read for everyone concerned about the definition and future of humanity. The Gene: An Intimate History (link to documentary here) in conversation with. The Gene: An Intimate History. The Gene: An Intimate History (PBS America) was Bruce’s latest, taking as its starting point the announcement by a Chinese researcher in 2018 that he had altered the genetic code of twin girls … That idea escalates to its macabre zenith in Nazi Germany in the 1940s, where human eugenics is used to justify grotesque experiments, culminating in confinement, sterilization, euthanasia, and mass murder. High street genetic tests – Dr Michael Mosley reports. The Gene, An Intimate History by Siddhartha Mukherjee Scribner, New York, 2016 Arthur L. Caplan1 Division of Medical Ethics, New York University Langone Medical Center, New York, New York, USA When you have written a best-selling, Pulitzer Prize-winning book, your next book is going to garner a great deal of attention. PBS announced KEN BURNS PRESENTS THE GENE: AN INTIMATE HISTORY, a new three-hour documentary executive produced by Ken Burns, … These efforts reach their crescendo in the Human Genome Project, an international project to map and sequence the entire human genome. The Gene: An Intimate History weaves together science, history & personal stories for a historical biography of the human genome, while also exploring breakthroughs for diagnosis & treatment of genetic diseases & the complex ethical questions they raise. Our daily newsletter arrives just in time for lunch, offering up the day's biggest science news, our latest features, amazing Q&As and insightful interviews. Sign up for our newsletter to stay updated. The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). Thanks! Gene Genetics history Schizophrenia Siddhartha Mukherjee. As I write this, organisms endowed with genomes are learning to change the heritable features of organisms endowed with genomes. The Gene: An Intimate History by Siddhartha Mukherjee is a fascinating read about the journey scientists have traveled to unlock the mysteries of the gene, the master code that defines all forms of life. That is what is at the center of this story. George Orwell once wrote that whenever a critic uses the word human, he usually renders it meaningless. Read an extract from Pulitzer Prize-winning author Siddhartha Mukherjee's and Wellcome Book Prize shortlisted history of the gene, all the way from Aristotle to the Human Genome Project. Listen to some of the brightest names in science and technology talk about the ideas and breakthroughs shaping our world. The gene defines who we are but at the same time is not definitive. Being a former teacher of Human Anatomy including Genetics, I am aware of the vastness of the subject and its branches but this book covers all the important aspects in less than 600 pages. The weight of heredity is not an abstraction for me. Described by the U.K.'s The Telegraph as “serious-minded, informative, and knowledgeable” in its four-star review, the lauded documentary The Gene: An Intimate History – co-produced by legendary documentarian Ken Burns – will enjoy a special virtual presentation on November 19 courtesy of the Quad Cities' PBS station WQPT, with the event boasting a post-screening discussion Description xi, 594 pages, 8 unnumbered pages of plates : illustrations (some color) ; 25 cm Notes Includes bibliographical references (pages … Format Book Edition First Scribner hardcover edition. That is the case with The Gene, Siddhartha Mukherjee's sequel to his widely acclaimed exploration of cancer, The Emperor of All Maladies. * Some topics, such as genetically modified organisms (GMOs), the future of gene patents, the use of genes for drug discovery or biosynthesis, and the creation of new genetic species merit books in their own right, and lie outside the purview of this volume. Embedded in the history of the gene is “the quest for eternal youth, the Faustian myth of abrupt reversal of fortune, and our own century’s flirtation with the perfectibility of man.” Embedded, equally, is the desire to decipher our manual of instructions. Two technologies transform genetics in the 1970s: gene sequencing and gene cloning—the “reading” and “writing” of genes (the phrase gene cloning encompasses the gamut of techniques used to extract genes from organisms, manipulate them in test tubes, create gene hybrids, and produce millions of copies of such hybrids in living cells.) This book is organized both chronologically and thematically. Scarcely a day passes in my adult life when I do not think about inheritance and family. A chain of post–World War II discoveries launches a revolution in biology. The three-letter genetic code is deciphered. Ken Burns Presents The Gene: An Intimate History The Gene: An Intimate History is a four-hour documentary from Ken Burns and Barak Goodman, adapted from the award-winning book of the same name by Dr. Siddhartha Mukherjee. THE GENE An Intimate History By Siddhartha Mukherjee 592 pp. The Gene: An Intimate History weaves together science, history & personal stories for a historical biography of the human genome, while also exploring breakthroughs for diagnosis & treatment of genetic diseases & the complex ethical questions they raise. This is not a story of our distant future; it is already embedded in our present). The Gene, An Intimate History by Mukherjee, Siddhartha Scribner, New York ... Pulitzer Prizewinning book, your next book is going to garner a great deal of attention. The series tells the story of the rapid evolution of genetic science from Gregor Mendel’s groundbreaking experiment in the 19th century to CRISPR, the family of DNA sequences found in the genomes of … Matthew Cobb - University of Manchester professor, author of Life’s Greatest Secret, and on-screen expert in The Gene- Moderated by Richard Sever, Ph.D. - Organized by Ludmila (Mila) Pollock, M.L.S. Thrive shows new and veteran teachers alike how to overcome the challenges and…, PGS Catalog is an open database of polygenic scores and the relevant metadata…, Joy McCann’s Wild Sea, the remarkable story of the world’s remote…, Internet is huge! "Sid Mukherjee has the uncanny ability to bring … Look out for your Lunchtime Genius newsletter in your inbox soon. Even before the beginning of human history, people recognized that parents transmit something — call it … The genome project, in turn, inspires attempts to understand human variation and “normal” behaviour in terms of genes. She weathered the buffets of history with resilience—but she weathered the buffets of heredity with something more than resilience: a grace that we, as her descendants, can only hope to emulate. Rajesh and Jagu are dead. For more information about how to do this, and how Immediate Media Company Limited (publisher of Science Focus) holds your personal information, please see our privacy policy. The gene provides an organizing principle for modern biology—and it tantalizes us with the prospect of controlling our bodies and fates. Monster by monster, evolution advanced’ The Gene: An Intimate History. Published New York : Scribner, 2016. She did not—she could not—outlive the grief of her inheritance, but she embraced and defended the most fragile of her children from the will of the strong. The overall arc is historical. The gene : an intimate history / Siddhartha Mukherjee. We can now “read” human genomes, and we can “write” human genomes in a manner inconceivable just three or four years ago. Today’s digital tech doesn’t replace human interaction – and that will lead to innovation. The “action” of a gene is described in mechanistic terms: genes encode chemical messages to build proteins that ultimately enable form and function. By clicking “sign up” you are agreeing to our terms and conditions and privacy policy. Once we can understand the nature of fate encoded by individual genomes (even if we can predict this in likelihoods rather than in certainties) and once we acquire the technology to intentionally change these likelihoods (even if these technologies are inefficient and cumbersome) our future is fundamentally changed. Scribner, 2017. In the 1980s, human geneticists begin to use these techniques to map and identify genes linked to diseases, such as Huntington’s disease and cystic fibrosis. There are stories within each of these stories, but this book is also a very personal story—an intimate history. Powerful personal stories and stunning breakthroughs reveal the historical search for the human genome and the promise of modern research. The story intersects with Darwin’s theory of evolution. With David Costabile, Edward Wild. I mean the following: in just the last four years—between 2012 and 2016—we have invented technologies that allow us to change human genomes intentionally and permanently (although the safety and fidelity of these “genomic engineering” technologies still need to be carefully evaluated). At the same time, the capacity to predict the future fate of an individual from his or her genome has advanced dramatically (although the true predictive capacities of these technologies still remain unknown). Visit website Share. This is the most crucial science of our time, intimately explained by a master. From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a…. From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). Are we ready to become X-Men or Avengers? The Gene: An Intimate History is a two-part series that explores the role of genetics in revolutionizing medical science. Is it possible for your head to be too heavy? Help us find great content. Most important, I owe a debt to my grandmother. Moni is confined to a mental institution in Calcutta. We begin in Mendel’s pea-flower garden, in an obscure Moravian monastery in 1864, where the “gene” is discovered and then quickly forgotten (the word gene only appears decades later). See the full shortlist at the bottom of this article, but first read the prologue of The Gene, a magnificent history of the gene by Pulitzer Prize-winning and New York Times bestseller Siddhartha Mukherjee. The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prize–winning author of The Emperor of All Maladies —a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). The gene provides an organizing principle for modern biology—and it tantalizes us with the prospect of controlling our bodies and fates. Sign in to manage your newsletter preferences. Each Part, there are stories within each of these stories, but this book is.! Accelerate human evolution and emancipation understanding of that disease to some of the gene and a…! In my adult life when I do not think about inheritance and family mental institution Calcutta! 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